Shocking Revelations About Aluminum: Scientists Link it to Alzheimer’s Disease! Time to Avoid This Metal As Much as Possible!
Most people don’t know that aluminium is a poison for the brain and the nervous system. It is actually a neurotoxin. Many experts have had claimed for a long time about the role of the metal in Alzheimer’s disease. The growing amount of evidence now indicates this more clearly.
The good thing is that there is also ample evidence suggesting that several natural plant extracts and nutrients are effective in the prevention and reduction of aluminium toxicity in your brain. They can also help in preventing the progression of memory loss and various cognitive deficits too.
Connection Between Alzheimer’s Disease & Aluminum
Dr. Walter Lukiw and his team of neuroscientists have been studying aluminum’s possible contribution to the onset, development and progression of the condition for almost 3 decades. Dr. Walter is PhD, Professor of Neurology, Neuroscience and Ophthalmology at Louisiana State University.
After years of research, the team of researchers has come to a summary that links aluminum and Alzheimer’s disease. It was reported in a peer-reviewed article in the Frontiers in Aging Neuroscience.
According to their summary, the contribution of aluminum to Alzheimer’s disease has minimum of 7 independently derive observations. They have listed these 7 evidences as following:
1. Aluminum causes strong promotion of beta-amyloid plaques in the brain. The levels have been found to be matching the current levels in humans.
2. It increases pro-inflammatory molecule called nuclear factor kappa beta or NF-kB to promote inflammation in the brain. This is a prominent feature found in the brains of those having Alzheimer’s disease.
3. Aluminium specifically increases the brain gene messenger RNA molecules which are found to be increased in Alzheimer’s disease. There are thousands of these molecules for conveying genetic information from DNA for gene expression. But the metal increases only these specific molecules linked Alzheimer’s disease.
4. Addition of aluminium to animal diets (where the animals had Alzheimer’s disease) found that there’s additional brain changes linked to the disease like programmed cell death, oxidative stress and deficits in gene expression.
5. The metal caused cellular energy deficits as linked with Alzheimer’s disease. Observations included impaired signaling associated with energy and ATP utilization.
6. A considerable number of studies have linked aluminum content in drinking water with occurrence of Alzheimer’s disease. Aluminum gets added to drinking water across the world as ‘finishing’ agent or clarification.
7. A chelation that uses an aluminum chelator is among the most effective therapeutic strategies so far compared to all the drug treatments for Alzheimer’s disease.
Animal Study Findings
When it comes to humans, it is not possible to conduct any ethically acceptable and direct tests to determine relation between aluminum and Alzheimer’s disease. Humans cannot be ethically dosed with aluminum. So, researchers have to find other scientific methods of investigation for learning the role of the metal in the case of this devastating disease. That is where animal studies come into the picture.
Studies on animals have proven the direct link between aluminum and Alzheimer’s disease in animals, even in extremely low doses. It can cause behavioral problems, memory impairment, and learning deficits. The rats tested to consume the equivalent amounts of aluminum as ingested by Americans from standard food and water, were found to develop severe Alzheimer’s-kind of cognitive deterioration when they reached old age.
The animals which were exposed to the metal were found to have definitive evidence of Alzheimer’s disease developed in their brains. It was much more than just developing symptoms which were Alzheimer’s-like.
The findings from these animal studies were as following:
– It gets accumulated in the brains cells in specific regions which are most likely to get damaged in Alzheimer’s disease.
– There are various studies that have shown aluminum causing abnormal formation of beta-amyloid plaques in animal brains. The plaques are considered as the hallmark signs of Alzheimer’s disease. They are formed when beta-amyloid (pieces of sticky proteins) get clumped and cause blockage of cell-to-cell signaling at synapses. They also cause activation of immune system cells which further trigger inflammation and lead to devouring of disabled cells. It is important to note that the aluminum-induced beta-amyloid plaques are formed in the same regions in the brain in animals as in the case of humans.
– There is another brain change found in the animals which get exposed to aluminum. This changes is also related to Alzheimer’s disease. It is the formation of neurofibrillary tangles. These are abnormal collections of twisted protein threads within nerve cells. They are mostly made up of a protein known as tau. Neurofibrillary tangles are just like beta-amyloid plaques in damaging the neuron-to-neuron ability for communication. They are also one of the hallmark features of Alzheimer’s disease.
What Do Prominent Researchers Have to Say?
There has been a spurt in the release of research findings by researchers from different parts of the world. There have been many recent published papers by different teams. they have outlined convincing evidence based on both animal and human studies. They have also warned about the dangers of aluminum, claiming it to be a cause of Alzheimer’s disease.
It is worth considering to know what has been claimed by certain experts about the link between aluminum and Alzheimer’s disease.
– According to J.R. Walton of the Faculty of Medicine, University of New South Wales, St George Hospital, Sydney, the evidence shows that Alzheimer’s disease is chronic aluminum neurotoxicity in the human form.
– According to Stephen Bondy of the Environmental Toxicology Program, Center for Occupational and Environmental Health, Department of Medicine, University of California, aluminum is likely not as innocuous as it was earlier thought to be. He claims that it may actively promote both the onset and progression of Alzheimer’s disease.
– Lucija Tomljenovic, PhD. Of the University of British Columbia, Vancouver says that there is solid experimental evidence behind the hypothesis that has been floated so long about aluminum contributing to Alzheimer’s disease. According to her, there is need for taking urgent steps for reducing human exposure to it.
– According to Masahiro Kawahara of the Department of Analytical Chemistry, School of Pharmaceutical Sciences, Kyushu University of Health and Welfare, Japan, there is commonly accepted that aluminum can not only cause dementia and cognitive deficiency, it is also a recognized neurotoxin. He claims that now there’s mounting amount of evidence that aluminum and Alzheimer’s disease are linked.
– According to Maire Percy, PhD of the University of Toronto, the hypothesis of link between aluminum toxicity and Alzheimer’s disease continues to be supported by more and more scientific publications. She says it will be best to implement strategies that prevent excess exposure to aluminum.
Alzheimer’s Patient & Presence of Aluminum in Brain
Dr. Christopher Exley (PhD, Keel University, UK) is one of the top researchers of the world who are studying the negative health effects of aluminum. According to his team, aluminum has been found to build up in the brain with age.
According to their latest research, many individuals above 70 have a possibly pathological amount of accumulation of aluminum in their brains.
In fact, Dr. Exley’s team have been the first ones to show recently elevated levels of aluminum in the brain of a person who was diagnosed with early-onset Alzheimer’s disease after getting occupational exposure to it.
Researchers have already linked occupational exposure to this metal with impaired cognitive function. Many studies show that increased exposure to aluminium caused people to perform poorly in tests involving various cognitive functions and memory.
In Dr. Exley’s study, a man (58 years old) who was previously healthy was diagnosed with Alzheimer’s disease after getting exposed to aluminum sulfate dust for 8 years. The initial complaints of the man included headaches, mouth ulcers and tiredness. Gradually, he began showing memory problems and depression. Then he was diagnosed with the disease.
The man died in 2011. When the man’s cerebral cortex was examined, it had significant amounts of beta-amyloid plaques and neurofibrillary tangles. This was in line with advanced Alzheimer’s disease.
Both the local coroner and his family requested his brain tissue samples to be sent for aluminum analysis with Dr. Exley. It was an opportunity for Dr. Exley and his team because it’s almost impossible to get access to this much brain tissue for the purpose of analysis. This led to the most comprehensive analysis of aluminium content in a brain region.
All the data established that there was aluminium accumulation in the brain tissue of the main. Certain frontal lobe samples showed excess aluminum levels which were adequately high for causing Alzheimer’s disease. This data can however not be considered as the proof of aluminum causing the aggressive Alzheimer’s disease in the man. But Dr. Exley claims that it quite possible because of the well-established neurotoxicity of aluminum.
Reducing Risk of Aluminum-Induced Alzheimer’s disease
The amount of evidence showing link between Alzheimer’s disease and aluminum continues to grow every day. It is time everyone should take steps at the personal level for minimizing aluminum exposure. It is also important to reduce the amount of aluminum that is already present in our body. There are many natural compounds that can help in not just reducing this burden of aluminum but also in preventing or treating the toxic effects of this ubiquitous metal.
Other included sources linked in Family Life Goals’s article: